Quantifying Behavioral Structure and Persistence in Open-Field Assays Using Entropy and Spectral Metrics

This paper introduces a high-throughput framework that integrates 3D pose estimation with unsupervised hidden Markov modeling to transform rodent open-field behavior into discrete syllables, utilizing Shannon entropy and spectral eigenvalue metrics to quantify the organization and temporal persistence of spontaneous behavior as a stochastic dynamical system.

Lee, S., Fu, Z., Choi, S.2026-03-09📄 animal behavior and cognition

Rejuvenation of the Aged Cerebrovascular System via Protein Corona-Guided Fusogenic Liposome Delivery

This study demonstrates that resveratrol-loaded, ApoE-enriched fusogenic liposomes effectively target the aged cerebrovascular system by directly fusing with endothelial membranes, thereby rejuvenating vascular function and cognitive performance in aged mice at doses 2000-fold lower than oral administration.

Shanmugarama, S., Gronemann, T., Csik, B. + 33 more2026-03-09📄 animal behavior and cognition

Bumble bees that follow a stricter routine innovate less: Foraging behaviors, environmental complexity, and how they relate to novel problem solving

This study demonstrates that while environmental complexity hinders bumble bees' initial detection of novel flowers, individual foraging traits—specifically faster movement and a lower tendency to form fixed routines—are the primary predictors of their success in solving novel foraging problems.

McWaters, S. R., Kearsley, J. J., Kikuchi, D. W. + 2 more2026-03-09📄 animal behavior and cognition

Intergenerational shifts in innate odour preferences upon odour injections in Bicyclus anynana butterfly larvae

This study demonstrates that while direct haemolymph injections of isoamyl acetate (IAA) can induce concentration-dependent preference or avoidance in *Bicyclus anynana* larvae that are subsequently inherited by their offspring, the molecule itself is not directly implicated in the intergenerational transmission of these learned odour preferences.

Chua, Y.-L., Gowri, V., Chan, I. Z. W. + 1 more2026-03-09📄 animal behavior and cognition

The Role of Magnetic and Celestial Cues in Orientation and Navigation of Red Underwing (Catocala nupta), a European Migratory Moth

This study demonstrates that the migratory red underwing moth (*Catocala nupta*) relies on a stellar compass for directional orientation but lacks a magnetic map for positional navigation and does not utilize magnetic cues for compass orientation in the absence of visual information.

Pakhomov, A., Dreyer, D., Zechmeister, T. + 2 more2026-03-07📄 animal behavior and cognition

Interspecific variation in cleaning behaviour and cheating among coral reef cleaner fishes

This study reveals that dedicated and non-dedicated coral reef cleaner fish exhibit distinct interspecific variations in cheating behavior and responses to social context, with specific species like *Labroides bicolor* adjusting their exploitation strategies based on client type and the presence of bystanders, thereby highlighting species-specific strategies that influence mutualism stability.

Romeo, D., Ranucci, M., Court, M. + 3 more2026-03-06📄 animal behavior and cognition

Persist or Give up? Fire ants motivated to search for a high-quality food source even if they don't know how to find it

This study demonstrates that while Solenopsis xyloni fire ants rely heavily on pheromone trails for navigation and often abandon foraging when trails are disrupted, the presence of a high-quality food source significantly increases their persistence in attempting to reach the resource despite the lack of navigational cues.

Joshi, C. H., Dornhaus, A.2026-03-06📄 animal behavior and cognition

AI-powered playbacks engage in flexible vocal interactions with zebra finches

This study demonstrates that zebra finches exhibit flexible, contingent vocal interactions with a real-time AI model (ZF-AIM), revealing that predictive timing drives responsiveness while acoustic structure is essential for vocal flexibility, thereby establishing a powerful framework for investigating animal communication dynamics.

James, L. S., Hoffman, B., Liu, J.-Y. + 10 more2026-03-06📄 animal behavior and cognition

Different Paradigms from Computer Vision Align with Human Assessment of the Mouse Grimace Scale

This study bridges the gap between automated computer vision and human assessment of the Mouse Grimace Scale by evaluating three dominant paradigms, demonstrating that they achieve reliable binary classification of mouse well-being with low error rates while focusing on relevant facial features beyond the traditional scale.

Reimann, M., Aloui, J., Obländer, N. + 4 more2026-03-06📄 animal behavior and cognition

From wag to affect: Tail kinematic signatures of canine emotional states in computer-controlled environments

This study utilizes computer-controlled tasks and pose-tracking to reveal that while dogs are more likely to wag their tails during positive anticipation, tail kinematics in negative contexts reflect arousal rather than valence, suggesting that tail wagging may be primarily a social signal rather than a universal indicator of emotional state.

Ouchi, Y., Glynn, C., Canori, C. + 4 more2026-03-05📄 animal behavior and cognition

Acquisition and extinction of drug-context memories are linked to distinct epigenetic and transcriptional mechanisms in the mouse dentate gyrus

This study demonstrates that in the mouse dorsal dentate gyrus, the acquisition and extinction of cocaine-context memories engage fundamentally distinct, non-overlapping epigenetic and transcriptional mechanisms, providing a molecular basis for why extinction suppresses rather than erases drug memories.

Baker, M. R., Sciortino, R., Zarley, C. + 4 more2026-03-05📄 animal behavior and cognition

A Multidimensional Framework for Behavioral Persistence: Dissociable Dimensions of Effort, Endurance, and Sequence Stability in Mice

This study introduces the PERCS framework to deconstruct behavioral persistence into five dissociable dimensions, demonstrating through mouse operant conditioning that unrewarded effort, rather than reward delivery, drives persistent behavior and that distinct task schedules differentially shape these dimensions to reveal stable phenotypic profiles.

Cao, T., Johnston, W. R., Christensen, S. + 2 more2026-03-05📄 animal behavior and cognition